Postnatal construction of neural circuitry in the mouse olfactory bulb
نویسندگان
چکیده
منابع مشابه
Postnatal construction of neural circuitry in the mouse olfactory bulb.
We have undertaken a quantitative analysis of the mouse olfactory bulb to address several major questions concerning the development of neural circuitry in the postnatal mammalian brain. These are: (1) To what degree are new elements and circuits added during maturation? (2) How long do such processes go on? and (3) Does postnatal development involve a net addition of circuits and their constit...
متن کاملOdorant receptors in the formation of the olfactory bulb circuitry.
In mammals, smell is mediated by odorant receptors expressed by sensory neurons in the nose. These specialized receptors are found both on olfactory sensory neurons' cilia and axon terminals. Although the primary function of ciliary odorant receptors is to detect odorants, their axonal role remains unclear but is thought to involve axon guidance. This review discusses findings that show axonal ...
متن کاملChanges in the neural representation of odorants after olfactory deprivation in the adult mouse olfactory bulb.
Olfactory sensory deprivation during development has been shown to induce significant alterations in the neurophysiology of olfactory receptor neurons (ORNs), the primary sensory inputs to the brain's olfactory bulb. Deprivation has also been shown to alter the neurochemistry of the adult olfactory system, but the physiological consequences of these changes are poorly understood. Here we used i...
متن کاملSynaptic circuitry of the retina and olfactory bulb.
The retina and olfactory bulb offer unique windows on the synaptic mechanisms of the brain. The wiring of both structures is known in detail and the sensory input can be quantitatively controlled. Synaptic operations can be examined in a clear functional context, for the nature of the information being processed is well-defined. The performance of the networks is remarkable. Rod photoreceptors ...
متن کاملPostnatal Development of Dendrodendritic Inhibition in the Mammalian Olfactory Bulb
The mitral-granule cell (MC-GC) reciprocal synapse is an important source of auto- and lateral-inhibition in the olfactory bulb (OB), and this local inhibition is critical for odor discrimination. We may gain insight into the role of MC autoinhibition in olfaction by correlating the functional development of the autoinhibition with the postnatal development of olfactory function. We have studie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1990
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.10-06-01952.1990